Harmful Reactions to Prescriptions Drugs: What it Can Do to your Body
Receiving a prescription drug or over the counter drug is supposed to help mend the body of whatever ails it, however, when the body reactions violently to the drugs consumed the result can be deadly. Each year thousands of Americans suffer from what is described as adverse drug reactions to prescription and over the counter drugs. The U.S. Food and Drug Administration has even acknowledged that anywhere from 3 to 11 percent of individuals are hospitalized each year because of an adverse drug reaction.
Stevens - Johnson Syndrome (SJS), and Toxic Epidural Necrolysis Syndrome (TEN) another form of SJS, are severe, adverse skin reactions to both prescription and over the counter medications. Many different drugs can trigger SJS, but anti-convulsants, antibiotics and anti-inflammatory drugs are most consistently responsible for causing SJS. While anyone can develop SJS, a Caucasian predominance has been reported. It is most commonly seen in children and in women (a 2:1 ratio compared to men), if untreated, will result in death. It is possible for those who are diagnosed with SJS to die and anywhere from 3 to 15 percent of victims have suffered this consequence. Additionally, over half the people who develop SJS experience serious upper respiratory tract infections.
What is known as Stevens-Johnson Syndrome, which was discovered in 1922, is a painful skin disease marked by ulcerated lesions found on the skin of a patient. According to the Stevens - Johnson Syndrome Foundation, the symptoms of SJS include:
. Rash, blisters or red splotches on the skin.
. Persistent fever.
. The body can form blisters and lesions anywhere from the genital area to the mouth, nose, eyes and even ears.
. Swelling of eyelids and/or red eyes.
. Conjunctivitis.
. Flu-like symptoms.
Patients with these symptoms have a recent history of having taken a prescription or over the counter medication.
Various prescription drugs have been found to be strongly associated with SJS, and some have even been recalled by the FDA. Non-steroidal anti-inflammatory drugs (NSAIDs) have recently come under a great deal of scrutiny relative to causing SJS. One such drug is Bextra, an anti-inflammatory drug prescribed to treat the pain associated with osteo-arthritis and rheumatoid arthritis. All of these drugs now have recently strengthened the warning and precautions sections of their packaging. Most are now required to have a "black box" warning, the highest warning level the FDA issues on approved drugs. The FDA has recalled or requested the manufacturer voluntarily remove these NSAIDs from the market.
While it is impossible to prevent the development of SJS, short of never taking any needed prescription or over the counter medication, there are ways to treat the disease if one does develop symptoms. It is of the utmost necessity to stop taking the drug associated with the negative side effects/reactions. After that, hospitalization is usually necessary, combined with a variety of treatment options including care from burn units, the ICU and dermatological teams. Individuals suffering from SJS who receive prompt and thorough treatment will likely successfully recover from the illness.
Stevens - Johnson Syndrome (SJS), and Toxic Epidural Necrolysis Syndrome (TEN) another form of SJS, are severe, adverse skin reactions to both prescription and over the counter medications. Many different drugs can trigger SJS, but anti-convulsants, antibiotics and anti-inflammatory drugs are most consistently responsible for causing SJS. While anyone can develop SJS, a Caucasian predominance has been reported. It is most commonly seen in children and in women (a 2:1 ratio compared to men), if untreated, will result in death. It is possible for those who are diagnosed with SJS to die and anywhere from 3 to 15 percent of victims have suffered this consequence. Additionally, over half the people who develop SJS experience serious upper respiratory tract infections.
What is known as Stevens-Johnson Syndrome, which was discovered in 1922, is a painful skin disease marked by ulcerated lesions found on the skin of a patient. According to the Stevens - Johnson Syndrome Foundation, the symptoms of SJS include:
. Rash, blisters or red splotches on the skin.
. Persistent fever.
. The body can form blisters and lesions anywhere from the genital area to the mouth, nose, eyes and even ears.
. Swelling of eyelids and/or red eyes.
. Conjunctivitis.
. Flu-like symptoms.
Patients with these symptoms have a recent history of having taken a prescription or over the counter medication.
Various prescription drugs have been found to be strongly associated with SJS, and some have even been recalled by the FDA. Non-steroidal anti-inflammatory drugs (NSAIDs) have recently come under a great deal of scrutiny relative to causing SJS. One such drug is Bextra, an anti-inflammatory drug prescribed to treat the pain associated with osteo-arthritis and rheumatoid arthritis. All of these drugs now have recently strengthened the warning and precautions sections of their packaging. Most are now required to have a "black box" warning, the highest warning level the FDA issues on approved drugs. The FDA has recalled or requested the manufacturer voluntarily remove these NSAIDs from the market.
While it is impossible to prevent the development of SJS, short of never taking any needed prescription or over the counter medication, there are ways to treat the disease if one does develop symptoms. It is of the utmost necessity to stop taking the drug associated with the negative side effects/reactions. After that, hospitalization is usually necessary, combined with a variety of treatment options including care from burn units, the ICU and dermatological teams. Individuals suffering from SJS who receive prompt and thorough treatment will likely successfully recover from the illness.
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