Near-Complete Resection of Brain Tumors Using Tumor Paint
Near-Complete Resection of Brain Tumors Using Tumor Paint
We have demonstrated as a proof-of-concept that it is possible to use a standard CCD for recording fluorescence from brain tumor using BLZ-100, a tumor ligand conjugated to ICG. This will enable us to reduce the size and cost of the imaging system. The use of a narrow-band laser at the peak absorption of ICG allows us to use low excitation fluence, and use of a narrow notch filter in front of the sensor will allow us to gather maximum fluorescence.
Conclusions
We have demonstrated as a proof-of-concept that it is possible to use a standard CCD for recording fluorescence from brain tumor using BLZ-100, a tumor ligand conjugated to ICG. This will enable us to reduce the size and cost of the imaging system. The use of a narrow-band laser at the peak absorption of ICG allows us to use low excitation fluence, and use of a narrow notch filter in front of the sensor will allow us to gather maximum fluorescence.
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